Monkeys that received an experimental vaccine for COVID-19 produced an immune response after a single shot, according to a study published in Nature. Researchers at Jannsen Vaccines and Prevention in Leiden, the Netherlands, and from Beth Israel Deaconess Medical Center in Boston, Massachusetts, gave 32 rhesus macaques a single dose of one of seven different versions of the vaccine candidate and 20 of them a placebo dose.
The vaccine uses a common cold virus, called adenovirus serotype 26 (Ad26), to deliver the SARS-CoV-2 spike protein into host cells, where it stimulates an immune response against SARS-CoV-2, the virus that causes COVID-19.
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